THE NIDUS OF TUBERCULOUS INFECTION AS A RISK FACTOR OF MULTIPLE DRUG RESISTANT TUBERCULOSIS IN CHILDREN
https://doi.org/10.21292/2075-1230-2018-96-1-11-17
Abstract
The article presents a comprehensive description of tuberculous infection nidi, where children were exposed to this infection and developed multiple drug resistant tuberculosis. It was found out that the risk to develop MDR TB in children was also related to exposure to a TB case with undetected resistance to rifampicin, which was to be taken into account when prescribing the chemotherapy regimen.
When prescribing preventive treatment to children exposed to MDR tuberculosis one should consider the potential risks and benefits.
About the Authors
V. A. Аksenovа
National Medical Research Center of Phthisiopulmonology and Infectious Diseases
Russian Federation
Russian Federation
Doctor of Medical Sciences, Professor, Head of Tuberculosis Children and Adolescent Tuberculosis Department
4, Dostoevsky St., Moscow, 127473
N. I. Klevno
National Medical Research Center of Phthisiopulmonology and Infectious Diseases
Russian Federation
Russian Federation
Doctor of Medical Sciences, Leading Researcher of Tuberculosis Children and Adolescent Tuberculosis Department
4, Dostoevsky St., Moscow, 127473
S. M. Kаvtаrаshvili
National Medical Research Center of Phthisiopulmonology and Infectious Diseases
Russian Federation
Russian Federation
Doctor of Department for Children and Adolescents
4, Dostoevsky St., Moscow, 127473
A. V. Kаzаkov
I. M. Sechenov First Moscow State Medical University
Russian Federation
Russian Federation
Candidate of Medical Sciences, Associate Professor
2, Bd. 4, Bolshaya Pirogovskaya St., Moscow, 119991
A. D. Pаkhlаvonovа
I. M. Sechenov First Moscow State Medical University
Russian Federation
Russian Federation
Assistant of Phthisiopulmonology and Thoracic Surgery Department
2, Bd. 4, Bolshaya Pirogovskaya St., Moscow, 119991
References
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For citations:
Аksenovа V.A., Klevno N.I., Kаvtаrаshvili S.M., Kаzаkov A.V., Pаkhlаvonovа A.D. THE NIDUS OF TUBERCULOUS INFECTION AS A RISK FACTOR OF MULTIPLE DRUG RESISTANT TUBERCULOSIS IN CHILDREN. Tuberculosis and Lung Diseases. 2018;96(1):11-17. (In Russ.) https://doi.org/10.21292/2075-1230-2018-96-1-11-17
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